Paris: Chez Richard, Caille et Ravier, An VIII (1800). 8vo. [viii], 326 pp., including half-title and index. FIRST EDITION. An uncut copy in the original wrappers. Item #12953
First edition of what many consider Bichat's best work, the foundation of histology and tissue pathology. It is here that he classifies and describes twenty-one kinds of tissue and membranes, a generalization of Pinel's earlier work, according to their texture and properties. Bichat (1771-1802) is one of the fathers of histology. "Without benefit of the microscope, this French anatomist and physiologist established a system of normal and pathological structure based on the individual tissues rather than on organs as the important biological units" (Eimas).