London: Printed for W. Innys; J. Richardson; C. Davis; J. Clarke; R. Manby; and H.S. Cox, 1754. Two volumes in one. 4to. xiv, [xviii], 404; 338 pp. Contemporary calf, rebacked with the original spine laid down, morocco spine label; interior excellent. Ownership signatures on title (one dated 1782). Item #13384
Second edition in English. Originally printed in French in 1736 and first translated the following year, Astruc’s work on syphilis, acknowledged as the author’s finest accomplishment, is a milestone in the history of the disease. Of the many original contributions to the field of skin diseases, Astruc was the first to relate cutaneous lesions to the anatomical structures which were involved. Focusing on the history and progress of research, he here summarizes and clarifies all of the knowledge of syphilis up to his time, which he dates to 1494, after the return of Columbus from the New World.
Astruc (1684-1766) studied in Montpellier and Toulouse and later settled in Paris. He was well respected as a teacher and for his clinical skills. The present text remained the standard reference on the subject for over fifty years.