Observations on madness and melancholy....

London: J. Callow, 1809. 8vo. Contemporary full calf, worn, rebacked. Item #425

Second edition, greatly enlarged. The work deals primarily with the autopsies he performed on insane patients, from which he records what is now considered one of the first descriptions of syphilis in the brain. G&M, 4794.

Price: $950.00

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